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PKA phosphorylates Myosin Binding Protein-C (MyBP-C) and troponin I (TnI) within the cardiac myofibril. TnI could be the inhibitory part on the trimeric troponin molecule that makes up the Ca2+-switch of the contractile apparatus. TnI binds to TnC when Ca2+ is bound to TnC, even though during the absence of Ca2+, the C-terminus of TnI is launched a